Obesity, fertility and in vitro fertilization

When couples try to increase their fertility opportunities, there are many factors to consider. They may be more aware of the food they eat, the intake of alcohol or caffeine, or the maintenance of exercise programs. Although these daily habits are definitely worth remembering, it is important to remember that a person's weight affects his or her overall health, and when it comes to fertility, weight is another potential that may affect success. factor.

To be pregnant, healthy weight is important. Being overweight or obese can affect your fertility. Obesity is a growing epidemic that affects the ability of obesity worldwide to significantly affect a woman's pregnancy to full-term. Obesity is defined by a very high body mass index [BMI], where the index is a reflection of body fat content. According to the survey and research, about a quarter of women are at least overweight. The proportion of women facing pregnancy problems is higher. Obese women are three times more likely to have infertility than women with normal body mass index. Overweight or obese women have a longer pregnancy time and a lower probability of conception than women of normal weight. In addition, they have an increased risk of early and repeated abortions. These women usually reduce oocyte quality, reduce developmental potential, and have poor clinical outcomes when performing adjuvant therapy.

“Healthy women have healthy eggs and are more likely to have healthy children,”

Obesity has different effects on male and female fertility as follows:

Obesity affects hormones
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  Hormone changes may occur in women when the body mass index exceeds the overweight category [BMI 25-29.9] into the obesity category [BMI 30 and above]. When the level of natural hormones changes, the chances of conception are reduced.

2. Obesity leads to insulin resistance
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  Hormonal disorders associated with obesity often lead to insulin resistance. This is a major risk factor for diabetes – but it also affects fertility and can lead to abnormal menstrual cycles. Insulin resistance can lead to anovulation, in which the body cannot spawn normally.

Obesity affects nature and assists pregnancy
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  Whether a couple uses natural or reproductive techniques, such as in vitro fertilization [IVF], obesity makes pregnancy more challenging. It also increases the risk of miscarriage. This problem may be caused by a hormonal problem, or it may be due to poor egg quality.

Obesity also affects male fertility
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  Although the focus on obesity and infertility is mainly on women, it has a large impact on men. For men, obesity causes a decrease in testosterone, which leads to infertility. Most importantly, obese men have a higher incidence of erectile dysfunction.

Losing weight can improve all of the above
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  In recent years, the link between lifestyle, weight, nutrition and fertility is gaining more public exposure. Multidisciplinary weight management methods are more likely to be a successful treatment option. Emphasis should be placed on lifestyle changes, education on proper diet, exercise and behavioural change. A more holistic approach to obesity and reproductive health can help increase the chances of conception for obese women. Doing so will also have a positive impact on overall health.

Due to weight loss, hormonal imbalances and other effects of obesity begin to decrease.

More specifically, the greater the female body mass index [BMI], the less likely she is to have a successful in vitro fertilization experience. A recent study shows that, to a large extent, today's generation is what their mothers and fathers eat before and around their concept. "This is a huge problem, and it can indeed achieve the next generation – maybe the next two generations."

Obesity has a negative impact on reproductive health. It has been determined that obesity and natural fertility are reduced, ovulation rate is reduced, pregnancy time is increased, and abortion rate is increased. In addition, increased complications of pregnancy, including pregnancy-induced hypertension, pre-eclampsia, gestational diabetes, postpartum hemorrhage, and large fetuses, are associated with obesity. As the incidence of obesity continues to rise, more and more overweight and obese women are seeking fertility treatment through assisted reproductive technology [ART].

There is nothing in the medical science that suggests that IVF cannot be used in obese or obese women. For obese women, IVF is still more complex and they require different drug doses than women of normal weight. Therefore, it is necessary to understand the full impact of obesity on in vitro fertilization [IVF] therapy. In vitro fertilization helps women become pregnant by mixing sperm and eggs outside the body and then implanting the embryos into the female uterus.

The following is the effect of obesity on the success rate of in vitro fertilization [IVF].

1. Obese women need higher doses of drugs: obesity is associated with higher doses of drugs that stimulate the ovaries. Obese women also need to take longer to cope, increase the cycle cancellation rate, and reduce the number of eggs removed.

2. Obese women are less likely to become pregnant: obese women have a lower IVF pregnancy rate. Due to the higher BMI, the chance of live birth after age adjustment is reduced. In other words, as women gain weight, the chances of having children are reduced.

3. Effects of obesity on eggs and embryos: The quality of eggs, fertilization rate and embryo quality of obese women decreased. This means that the retrieved eggs may cause the IVF cycle to fail. Due to the poor quality of eggs, obese women are less likely to obtain successful in vitro fertilization from their own eggs [rather than eggs]. Obese women clearly have a normal success rate when it comes to IVF administered to an egg. Obviously, women with a BMI of 25, especially those with a BMI > 30, have a poorer ovarian response to fertility drugs [following follicles and embryonic development, fewer blastocysts, and metastases are available]. Due to the reduced endometrial receptivity, these women tend to have reduced ability to implant metastatic embryos into the endometrium due to their thickness.

4. Obesity affects the lining of the uterus: obese women are more prone to abnormal thickening of the endometrium. This is because estrogen is excessively secreted in obese women. The endometrium thickens and is difficult for obese women to accept. Obviously, women with a BMI of 25, especially those with a BMI > 30, have a poorer ovarian response to fertility drugs [following follicles and embryonic development, fewer blastocysts, and metastases are available]. Due to the reduced endometrial receptivity, these women tend to have reduced ability to implant metastatic embryos into the endometrium due to their thickness.

Women who plan to become pregnant or enter the IVF program should recommend losing weight before starting because a very strict diet is not allowed during pregnancy or during IVF. The clinical significance of more and more overweight female patients is overwhelming, because it will not only threaten their overall reproductive ability, but also increase the risk of diabetes, coronary, brain/peripheral vascular disease and other chronic diseases, and endanger life. Expectation and quality of life. Therefore, overweight will cause an overall life-threatening problem and should be solved by the medical community and the whole society. The answer is certainly not a simple answer, but the solution is not to diet alone. Instead, it requires a comprehensive revision of the lifestyle.

It is worth noting that lowering BMI by weight loss has been shown to significantly improve fertility treatment and reduce treatment and pregnancy complications. In other words, obesity not only makes pregnancy more difficult, but also provides various risks for mothers and babies before and after birth.

The IVF Center in India is used for IVF, IUI, ICSI, surrogacy, egg and sperm donation. The clinic provides IVF [in vitro fertilization] treatment for infertile couples from all over the world. The clinic's expertise in fertility treatment and cutting-edge technology has helped most patients achieve pregnancy. Obese women who are recommended for fertility and infertility treatment lose weight and improve BMI. All options for pregnant women with obesity are explained in detail. Finally, it is important to emphasize that overweight women are at greater risk during pregnancy than women of normal weight. It is recommended that women who plan to become pregnant or enter the IVF program lose weight before starting because of weight loss "improving ovulation function" and pregnancy outcomes. It is worth noting that lowering BMI by weight loss has been shown to significantly improve fertility treatment and reduce treatment and pregnancy complications. In other words, obesity not only makes pregnancy more difficult, but also provides various risks for mothers and babies before and after birth. "Because of the complexity of obesity and reproduction, when the fertility of obese women is beneficial to fertility treatment, a personalized but systematic approach is needed.

Obesity, fertility and in vitro fertilization was originally published on Spring

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